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Ketamine hydrochloride produces dissociative anaesthesia characterised by catalepsy, amnesia, and marked analgesia which may persist into the restoration interval. Pharyngeal-laryngeal reflexes remain regular and skeletal muscle tone could additionally be normal or may be enhanced to various levels. Mild cardiac and respiratory stimulation and infrequently respiratory depression occur. When utilized by intravenous or intramuscular injection, Ketamine is greatest suited for brief procedures. With additional doses, or by intravenous infusion, Ketamine can be utilized for longer procedures. If skeletal muscle relaxation is desired, a muscle relaxant ought to be used and respiration ought to be supported. Effects are quick if injected, though this practice is rarer, with most users sniffing the drug. If sniffed, the consequences will take around 20 minutes to come back on, and might final mediumeasy for one or two hours. Some neonates exposed to ketamine at maternal intravenous doses ≥ 1...

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